DJ-1 products glycolic acid and D-lactate restore deficient axonal trafficking and DNA damage response in FUS and SOD1-associated amyotrophic lateral sclerosis
Arun Pal, Dajana Großmann, Hannes Glaß, Vitaly L. Zimyanin, René Günther, Marica Catinozzi, Tobias M. Boeckers, Jared L. Sterneckert, Erik Storkebaum, Susanne Petri, Florian Wegner, Stefan Grill, Francisco J. Pan-Montojo, Andreas Hermann
The paper shows that glycolic acid and D-lactate restore axonal trafficking and DNA damage response in FUS and SOD1-ALS patient-derived motoneurons.
bioRxiv · Sep 20, 2023 · PreprintNeuroscience