Renin is critical for Renin Lineage Cell Plasticity and Migration in experimental crescentic Glomerulonephritis
Shila Azizolli, Sagor Halder, Anne Steglich, Akua Annoh, Florian Gembardt, Irina Simonova, Jan Sradnick, Andreas Dahl, Rajinder Kumar Gupta, Stefan R. Bornstein, Vladimir Todorov, Hannah Weissbach, Christian Hugo
This study shows that renin in renin-lineage cells protects against crescentic glomerulonephritis by supporting cell migration and reducing inflammation.
Journal of the American Society of Nephrology · Aug 24, 2026Peer-reviewedPathology