Andreas Dahl

The paper shows that tissue composition at the amputation plane influences osteoclast-mediated skeletal resorption and regenerative strategies in axolotl limb regeneration.

This study shows that renin in renin-lineage cells protects against crescentic glomerulonephritis by supporting cell migration and reducing inflammation.

This study identifies Nup153's role in repressing neuronal genes through HDAC1-mediated epigenetic regulation, influencing chromatin states and neuronal responsiveness.

This study uses a cross-species bone marrow niche model to show that plasticity in the murine niche supports human HSC engraftment, highlighting its role in stem cell function.

This study identifies SYCP2's closure motif as essential for HORMAD2 recruitment to chromosome axes, revealing its role in meiotic synapsis quality control in mice.

The paper integrates single nuclei transcriptomics and spatial transcriptomics of human peripheral nerves to identify novel cell markers, reveal pan-nerve disease characteristics, and demonstrate potential for unbiased diagnostic classification.

This study identifies AZIN2 as a regulator of adipocyte progenitor fate through polyamine metabolism, showing its protective role against obesity and metabolic dysfunction.

This study identifies EGFL7 as a driver of immune evasion in glioblastoma by interacting with integrin β2, showing that targeting this axis enhances immunotherapy efficacy.

This study investigates the functional differences between thymic and peripheral Treg cells in visceral adipose tissue, showing that tTreg instability contributes to inflammation and obesity while pTreg cells protect against metabolic disorders.

The paper shows that passage 1 human iPSC-derived RPE cells form more extensive monolayers after transplantation compared to passage 2 cells, highlighting a subpopulation with higher transplantation potential.

The paper identifies H3K27me3 regulation of extra-cellular matrix composition in human corticogenesis using Epi-CyTOF and cortical organoids.

The paper identifies chromatin accessibility differences between renal cortex and inner medulla, showing their correlation with gene expression and modulation by NFAT5.

This study investigates how social environment affects Alzheimer's disease progression in App-NL-G-F mice, showing social deficits precede pathology and linking microglia activation to neuroinflammation and neurogenesis.

The paper investigates cell lineage relationships in zebrafish fin regeneration using single-cell RNA sequencing and lineage tracing, revealing compartmentalized osteoblast and blastema contributions to bone formation.

The paper uses single-cell RNA sequencing to study zebrafish retina regeneration, identifying transcriptional changes and fate decisions in Muller glia and progenitors.

This study shows that cellular senescence promotes progenitor cell expansion during axolotl limb regeneration by creating a pro-proliferative niche and modulating Wnt signaling.

The paper uses fate-mapping, single-cell RNA-sequencing, and computational methods to show that major hematopoietic lineages diverge within HSCs, identifying a self-renewing HSC subpopulation and a direct thrombopoiesis pathway.

This study shows that loss of SETD1B in oocytes causes redistribution of H3K4me3, with loss at active promoters and gain at CpG-rich regions, revealing distinct roles for SETD1B and MLL2 in epigenetic regulation.

This study uses multi-omics analysis of pancreatic islet donors to show heterogeneous beta cell changes associated with type 2 diabetes progression.

This study shows environmental enrichment counteracts age-related DNA methylation changes in the hippocampus of mice, preventing CpG hypomethylation at Mecp2 target sites and preserving neuronal functions.

The paper identifies high ROS levels in quiescent adult hippocampal stem cells and shows how physical activity triggers their activation through a Nox2-dependent ROS surge.

This study shows that MLL1 is essential for intestinal stem cell maintenance and regulates the expression of JAML, a cell adhesion molecule critical for stem cell niche interactions.

This paper introduces a methanol-responsive polymer (MeRPy) that selectively binds and releases DNA targets, improving NGS library quality by depleting unwanted transcripts.

The paper profiles miRNAs in mouse cortical progenitors and neurons, identifying miR-486-5p as a novel regulator of neurogenesis.

The paper uses RNAi screens in isogenic human stem cells to identify SMARCA4 as a differential regulator of stemness and differentiation in hematopoietic and neural stem cells.

The paper uses single-cell transcriptomics to analyze how Amyloid-beta42 and Interleukin-4 affect neural stem/progenitor cell plasticity in adult zebrafish brain, identifying gene expression changes and cell-cell communication alterations.

The paper identifies and characterizes circRNAs in developing mouse cortical progenitor cells, revealing nearly 4,000 new circRNAs and their expression patterns.

This study shows that IL4 restores neurogenic plasticity of human NSCs by suppressing KAT2, which is upregulated in AD mouse models.

This paper introduces a 3D hydrogel culture system to model human neural stem cell plasticity, neurogenesis, and neurodegeneration, showing improved neuronal maturation and disease modeling.