A prostaglandin F2 alpha analog protects from statin-induced myopathic changes in primary human muscle cells
Stefanie Anke Grunwald, Oliver Popp, Stefanie Haafke, Nicole Jedraszczak, Ulrike Grieben, Kathrin Saar, Giannino Patone, Wolfram Kress, Elisabeth Steinhagen-Thiessen, Gunnar A. G. Dittmar, Simone Spuler
This study shows statins alter gene and protein expression in human muscle cells, with a prostaglandin F2 alpha analog potentially mitigating these effects.
bioRxiv · Aug 15, 2019 · PreprintMolecular Biology