Gunnar A. G. Dittmar

The paper identifies VACs as specialized transport organelles delivering a preassembled apical cortex to the AMIS, enabling lumen initiation, and highlights PatJ's role in coordinating this process with cell-cell junctions.

This study shows DJ-1 affects metabolism and immune response differently in Parkinson's disease and glioblastoma cells, with antioxidant treatment rescuing PD-related phenotypes.

This study identifies Arl8b as a potential biomarker for Alzheimer's disease by analyzing proteomic changes in 5xFAD mouse brain regions and CSF from AD patients.

This paper maps the C/EBPα interactome using PRISMA and BioID, revealing PTM-dependent interactions and motifs that define its functional plasticity.

The paper uses machine learning to connect proteomics data with histopathology images in kidney cancer, finding correlations between proteins and imaging-based predictions.

This study shows statins alter gene and protein expression in human muscle cells, with a prostaglandin F2 alpha analog potentially mitigating these effects.

This study identifies SorCS2 as a regulator of EAAT3 trafficking that protects neurons from oxidative stress and epilepsy-induced damage.

The paper uses independent component analysis to analyze melanoma transcriptomic data, distinguishing biological signals from technical biases and identifying clinically relevant patient characteristics.

The paper introduces a drug sensitivity prediction system using a 47-gene expression profile derived from transcriptomic analysis, validated with independent datasets and showing high concordance with observed drug responses.