IRF8 deficiency causes anxiety-like behavior in a sex-dependent manner
Stella Zhu, Keita Saeki, Rose‐Marie Karlsson, Daniel T. Abebe, Keiko Ozato
This study shows that IRF8 deficiency in microglia causes anxiety-like behavior in female mice but not males, with redox dysregulation involved.
bioRxiv · Sep 2, 2025 · PreprintNeuroscience