Keita Saeki

This study shows that deep vein thrombosis primes neutrophils to promote brain metastasis in triple-negative breast cancer by enhancing their recruitment and NET formation.

This study identifies IRF8 as a B cell-intrinsic regulator of antigen presentation that sustains CD8⁺ T cell antitumor immunity and predicts response to PD-1 blockade therapy.

This study shows that IRF8 deficiency in microglia causes anxiety-like behavior in female mice but not males, with redox dysregulation involved.