Modular Derivation and Unbiased Single-cell Analysis of Regional Human Hindbrain And Spinal Neurons Enables Discovery of Nuanced Transcriptomic Patterns along Developmental Axes
Nisha R. Iyer, Junha Shin, Stephanie Cuskey, Yucheng Tian, Noah R. Nicol, Tessa E. Doersch, Sunnie Grace McCalla, Sushmita Roy, Randolph Scott Ashton
The paper develops a modular differentiation system to generate diverse human hindbrain and spinal neurons and uses computational methods to identify region-specific transcriptomic patterns.
bioRxiv · Oct 14, 2021 · PreprintNeuroscience