Nisha R. Iyer

This paper develops a low-cost, rapid method for fabricating PEG-based cell culture devices using 3D printing and PDMS molds, enabling customizable microphysiological systems for tissue engineering.

This paper develops a low-cost protocol to generate functional neurons from hiPSCs in 6 days using a TET-on NGN2 system and DAPT to enhance neurogenesis.

The paper develops a human microphysiological model of dorsal root ganglion-spinal cord dorsal horn circuitry that mimics opioid-induced effects through electrophysiological responses.

The paper introduces the RosetteArray platform for high-throughput screening of neurodevelopmental risk by culturing standardized neural rosettes from human pluripotent stem cells and analyzing them with AI.

The paper develops a modular differentiation system to generate diverse human hindbrain and spinal neurons and uses computational methods to identify region-specific transcriptomic patterns.

This paper optimizes the PACT clearing technique for 3D imaging of intact and injured mouse spinal cords to study neural circuits and SCI-related changes.