TRPA1 activation in non-sensory supporting cells contributes to regulation of cochlear sensitivity after acoustic trauma
Alejandra Catalina Vélez-Ortega, Ruben Stepanyan, Stephanie E. Edelmann, Sara Torres-Gallego, Channy Park, Desislava A. Marinkova, Joshua S. Nowacki, Ghanshyam P. Sinha, Gregory I. Frolenkov
This study shows TRPA1 activation in cochlear supporting cells leads to prolonged Ca2+ responses and contractions that affect cochlear sensitivity after acoustic trauma.
Nature Communications · Jun 30, 2023Peer-reviewedNeuroscience