Author

Gregory I. Frolenkov

University of KentuckyORCID 0000-0002-9810-5024Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Abigail K. DragichiD· 2 shared Shadan E. HadiiD· 2 shared Alejandra Catalina Vélez-OrtegaiD· 1 shared Arnaud P. J. GieseiD· 1 shared Benjamin J. PerriniD· 1 shared Channy ParkiD· 1 shared Craig W. Vander KooiiD· 1 shared Desislava A. Marinkova· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersNeuroscience

Abigail K. DragichORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 19, 2025

A Myosin Nanomotor Essential for Stereocilia Maintenance Expands the Etiology of Hereditary Hearing Loss DFNB3

Ghazaleh Behnammanesh, Abigail K. Dragich, Xiayi Liao…·Jonathan E. Bird

The paper identifies a new myosin isoform, MYO15A-3, essential for maintaining stereocilia structure in postnatal hair cells, contributing to DFNB3 hearing loss.

1 citation

mouseexperimental assay

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NeurosciencebioRxivPreprintJul 9, 2023

Calcium and Integrin-binding protein 2 (CIB2) controls force sensitivity of the mechanotransducer channels in cochlear outer hair cells

Isabel Aristizábal-Ramírez, Abigail K. Dragich, Arnaud P. J. Giese…·Gregory I. Frolenkov

This study investigates the role of CIB2 in mechanotransducer channels of cochlear outer hair cells, finding that a mutation alters channel properties and force sensitivity.

3 citations

mouseelectronic health records

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NeuroscienceNature CommunicationsPeer-reviewedJun 30, 2023

TRPA1 activation in non-sensory supporting cells contributes to regulation of cochlear sensitivity after acoustic trauma

Alejandra Catalina Vélez-Ortega, Ruben Stepanyan, Stephanie E. Edelmann…·Gregory I. Frolenkov

This study shows TRPA1 activation in cochlear supporting cells leads to prolonged Ca2+ responses and contractions that affect cochlear sensitivity after acoustic trauma.

18 citations

mouseexperimental assay

𝕏 PostBluesky