Structural and functional analysis of Pseudomonas aeruginosa PelA provides insight into the modification of the Pel exopolysaccharide
Jaime C. Van Loon, François Le Mauff, Mario A. Vargas, Stephanie Gilbert, Roland Pfoh, Zachary A. Morrison, Erum Razvi, Mark Nitz, Donald C. Sheppard, P. Lynne Howell
This study determines the structure of PelA and shows it modifies Pel through deacetylation and hydrolysis, with PelAB interaction enhancing deacetylation and guiding export.
Journal of Biological Chemistry · Mar 20, 2025Peer-reviewedMicrobiology