Author

Donald C. Sheppard

McGill UniversityORCID 0000-0001-8877-880XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

François Le MauffiD· 2 shared P. Lynne HowelliD· 2 shared Roland PfohiD· 2 shared D. RajuiD· 1 shared Daniel J. WozniakiD· 1 shared Daphnée LamarcheiD· 1 shared Erum RazviiD· 1 shared Gregory B. WhitfieldiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

François Le MauffORCID

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2 papers

Recent·Most cited

MicrobiologymBioPeer-reviewedJul 7, 2025

Autoaggregation in Streptococcus intermedius is driven by the Pel polysaccharide

D. Raju, Siobhán A. Turner, Karla Castro…·P. Lynne Howell

This study identifies the Pel polysaccharide as a driver of autoaggregation in S. intermedius, linking it to biofilm formation and increased pathogenicity.

3 citations

bacteria (other)experimental assay

𝕏 PostBluesky

MicrobiologyJournal of Biological ChemistryPeer-reviewedMar 20, 2025

Structural and functional analysis of Pseudomonas aeruginosa PelA provides insight into the modification of the Pel exopolysaccharide

Jaime C. Van Loon, François Le Mauff, Mario A. Vargas…·P. Lynne Howell

This study determines the structure of PelA and shows it modifies Pel through deacetylation and hydrolysis, with PelAB interaction enhancing deacetylation and guiding export.

4 citations

bacteria (other)experimental assay

𝕏 PostBluesky