Gut mucosal cells transfer alpha-synuclein to the vagus nerve
Rashmi Chandra, Arpine Sokratian, Katherine Ramos Chavez, Stephanie King, Sandip Madhusudan Swain, Joshua C. Snyder, Andrew B. West, Rodger A. Liddle
The paper shows that gut mucosal cells can transfer alpha-synuclein to the vagus nerve, suggesting a non-neuronal source of fibrillar alpha-synuclein in Parkinson's disease.
JCI Insight · Dec 7, 2023Peer-reviewedNeuroscience