Inhibition of the Adenosine pathway activates the immune response against Mesothelioma.
Caterina Costa, Steve Gray, Giulia Pinton, Laura Moro, Erika Del Grosso, Cristiana Bellan, Laura Addi, Rita Lombardi, Francesca Bruzzese, Davide De Biase, Biagio Pucci, Elena Di Gennaro, Paolo A. Ascierto, Giovanni Luca Gravina, Luciano Mutti
This study shows that inhibiting the adenosine pathway with AB680 or TT-4, alone or with anti-PD-1, reduces mesothelioma growth in vitro and in vivo.
bioRxiv · May 13, 2026 · PreprintCancer Biology