A human DNA methylation atlas reveals principles of cell type-specific methylation and identifies thousands of cell type-specific regulatory elements
Netanel Loyfer, Judith Magenheim, Ayelet Peretz, Gordon M. Cann, Joerg Bredno, Agnes Klochendler, Ilana Fox-Fisher, Sapir Shabi-Porat, Merav Hecht, Tsuria Pelet, Joshua Moss, Zeina Drawshy, Hamed Amini, Patriss Wais Moradi, Sudharani Nagaraju, , Tommy Kaplan
The paper constructs a human DNA methylation atlas using whole-genome bisulfite sequencing of 39 cell types, revealing cell type-specific methylation patterns and regulatory elements.
Nature · Jan 4, 2023Peer-reviewedGenomics