Author

Ayelet Peretz

Hebrew University of JerusalemORCID 0000-0002-0675-2436Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:DNA methylation· 3 Approach:statistical model· 3 Research Focus:database / resource· 2 Research Focus:differential expression· 2 Approach:deep learning· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Benjamin GläseriD· 4 shared Netanel LoyferiD· 4 shared Ruth ShemeriD· 4 shared Tommy KaplaniD· 4 shared Yuval DoriD· 4 shared Judith MagenheimiD· 3 shared Agnes KlochendleriD· 2 shared Arash JamshidiiD· 2 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenomics

Benjamin GläserORCID

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4 papers

Recent·Most cited

Time is encoded by methylation changes at clustered CpG sites

Bracha-Lea Ochana, Daniel Nudelman, Daniel Cohen, Ayelet Peretz, Sheina Piyanzin, Ofer Gal-Rosenberg, Amit Horn, Netanel Loyfer, Miri Varshavsky, Ron Raisch, Ilona Shapiro, Yechiel Friedlander, Hagit Hochner, Benjamin Gläser, Yuval Dor, , Ruth Shemer

The paper shows that DNA methylation changes at clustered CpG sites encode chronological age with high accuracy using deep learning on blood samples.

Cell Reports · Jul 1, 2025Peer-reviewedGenomics

Atlas of imprinted and allele-specific DNA methylation in the human body

Jonathan Rosenski, Ayelet Peretz, Judith Magenheim, Netanel Loyfer, Ruth Shemer, Benjamin Gläser, Yuval Dor, Tommy Kaplan

The paper creates a comprehensive atlas of allele-specific DNA methylation across 39 human cell types, identifying 325k genomic regions and 460 novel imprinted loci with cell-type-specific patterns.

Nature Communications · Mar 11, 2025Peer-reviewedGenomics

A human DNA methylation atlas reveals principles of cell type-specific methylation and identifies thousands of cell type-specific regulatory elements

Netanel Loyfer, Judith Magenheim, Ayelet Peretz, Gordon M. Cann, Joerg Bredno, Agnes Klochendler, Ilana Fox-Fisher, Sapir Shabi-Porat, Merav Hecht, Tsuria Pelet, Joshua Moss, Zeina Drawshy, Hamed Amini, Patriss Wais Moradi, Sudharani Nagaraju, , Tommy Kaplan

The paper constructs a human DNA methylation atlas using whole-genome bisulfite sequencing of 39 cell types, revealing cell type-specific methylation patterns and regulatory elements.

Nature · Jan 4, 2023Peer-reviewedGenomics

Remote immune processes revealed by immune-derived circulating cell-free DNA

Ilana Fox-Fisher, Sheina Piyanzin, Bracha-Lea Ochana, Agnes Klochendler, Judith Magenheim, Ayelet Peretz, Netanel Loyfer, Joshua Moss, Daniel Cohen, Yaron Drori, Nehemya Friedman, Michal Mandelboim, Marc E. Rothenberg, Julie M. Caldwell, Mark Rochman, , Yuval Dor

The paper uses immune cell type-specific methylation patterns in circulating cell-free DNA to monitor immune dynamics and find that immune-derived cfDNA levels reflect immune homeostasis and predict immune responses to perturbations.

eLife · Nov 26, 2021Peer-reviewedGenomics