Intrathecal (G4C2)149 delivery in C9orf72-deficient mice yields mild motor dysfunction and ALS/FTD pathological hallmarks
Katelyn A. Russell, Amelia A Shahrabi, Suleyman C. Akerman, Matthew D. Byrne, Jeffrey D. Rothstein, Davide Trotti, Brigid K. Jensen, Aaron R. Haeusler
This paper delivers (G4C2)149 repeats intrathecally in C9orf72-deficient mice, revealing mild motor dysfunction and ALS/FTD pathological features.
Acta Neuropathologica Communications · Jun 18, 2026Peer-reviewedNeuroscience