Author

Suman Shrestha

University of MainePrimary ORCID profile (0000-0002-7011-7496 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Suman ShresthaiD1 paper · University Health Network

Biology Disciplines

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Biophysics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 1 Approach:machine learning (classical)· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Organism:virus· 1

Frequent Co-Authors

Alexander J. SodtiD· 1 shared Bonny Wu· 1 shared Chamithri Weerakoon· 1 shared David WinskiiD· 1 shared Hang N. Waters· 1 shared Idorenyin A. IweiD· 1 shared Ilan Zeisler· 1 shared Jaqulin N. WallaceiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Alexander J. SodtORCID

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Author profile →

2 papers

Recent·Most cited

The Influenza Hemagglutinin Cytoplasmic Tail Domain Interacts with Phosphatidylinositol 4,5-bisphosphate

David Winski, Matthew T. Parent, Jaqulin N. Wallace, Chamithri Weerakoon, Suman Shrestha, Prakash Raut, Hang N. Waters, Joshua J. Zimmerberg, Alexander J. Sodt

This paper investigates the interaction between influenza HA's cytoplasmic tail domain and PIP2 using MD and FPALM, finding electrostatic and hydrophobic contributions to HA-PIP2 binding.

bioRxiv · Aug 26, 2026 · PreprintBiophysics

Minimal Data, Maximal Insight (MDMI): A Structure-guided Pipeline for Discovering Functional Alternatives in Peptide-Protein Interfaces

Pouriya Bayat, Spencer James Perkins, Sebastian Clancy, Sahil Swapnesh Patel, Richard Fei Yin, Krištof Bozovičar, Serena Singh, Suman Shrestha, Zain Moustafa, Riham Zayani, Idorenyin A. Iwe, Sepehr Bayat, Paul Kelly, Justin R. J. Vigar, Vivan Yuna White, , Keith Pardee

MDMI is a structure-guided pipeline that designs functional peptide variants from minimal data, achieving high accuracy and discovering divergent sequences with measurable activity.

bioRxiv · Jul 14, 2026 · PreprintSynthetic Biology