Multiplexed CRISPRi Reveals a Transcriptional Switch Between KLF Activators and Repressors in the Maturing Neocortex
Ryan W Kirk, Sun Liwei, Ruixuan Xiao, Erin Clark, Sacha B. Nelson
The paper identifies a transcriptional switch in KLF activators and repressors during postnatal neuronal maturation using CRISPRi and integrates chromatin and gene expression data.
eLife · Oct 20, 2026Peer-reviewedNeuroscience