Commensal-pathogen dynamics structure disease outcomes during Clostridioides difficile colonization
Skye R. S. Fishbein, Anna L. DeVeaux, Sakshi Khanna, Aura L. Ferreiro, James Liao, Wesley Agee, Jie Ning, Bejan Mahmud, Miranda J. Wallace, Tiffany Hink, Kimberly A. Reske, Candice Cass, Janaki L. Guruge, Sidh Leekha, Sunaina Rengarajan, , Gautam A. Dantas
The paper investigates why C. difficile colonization leads to varying disease outcomes by studying microbiota-humanized mice and identifying commensals that mitigate virulence.
Cell Host & Microbe · Dec 27, 2024Peer-reviewedMicrobiology