NeurosciencebioRxivPreprint
Methylglyoxal modification of TrkB promotes synaptic plasticity and enhances resilience to chronic stress
Ziyin Wu, Yingxue Fu, Yinfeng Yang…·Yonghua Wang
This study shows that methylglyoxal (MGO) enhances resilience to chronic stress and alleviates depression-like symptoms by promoting synaptic plasticity through TrkB activation and BDNF expression.
5 citations