Author

Ziyin Wu

Northwest A&F UniversityORCID 0000-0002-3382-2620Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Wei XiaoiD· 3 shared Yingxue FuiD· 3 shared Zhenzhong WangiD· 3 shared Zihu GuoiD· 3 shared Chao HuangiD· 2 shared Chunli ZhengiD· 2 shared Liyang CheniD· 2 shared Xuetong CheniD· 2 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersSystems Biology

Wei XiaoORCID

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3 papers

Recent·Most cited

Systems BiologyGenomics Proteomics & BioinformaticsPeer-reviewedMar 17, 2021

NOGEA: Network-Oriented Gene Entropy Approach for Dissecting Disease Comorbidity and Drug Repositioning

Zihu Guo, Yingxue Fu, Chao Huang…·Yonghua Wang

NOGEA identifies master genes driving disease initiation and comorbidity, predicts drug-disease associations, and validates new drug candidates for pancreatic cancer.

7 citations

humanstatistical model

𝕏 PostBluesky

BioinformaticsGenomicsPeer-reviewedNov 2, 2019

Systems-level analysis identifies key regulators driving epileptogenesis in temporal lobe epilepsy

Yingxue Fu, Ziyin Wu, Zihu Guo…·Yonghua Wang

This study identifies key regulators of epileptogenesis in temporal lobe epilepsy using systems-level analysis of transcriptomic data from rodent models and human patients.

21 citations

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 12, 2018

Methylglyoxal modification of TrkB promotes synaptic plasticity and enhances resilience to chronic stress

Ziyin Wu, Yingxue Fu, Yinfeng Yang…·Yonghua Wang

This study shows that methylglyoxal (MGO) enhances resilience to chronic stress and alleviates depression-like symptoms by promoting synaptic plasticity through TrkB activation and BDNF expression.

5 citations

ratexperimental assay

𝕏 PostBluesky