THE C99 FRAGMENT OF APP REGULATES CHOLESTEROL TRAFFICKING
Marta Pera, Delfina Larrea, Jorge Montesinos, Cristina Guardia‐Laguarta, Rishi R. Agrawal, KEVIN R. VELASCO, Yimeng Xu, SY Koo, Amanda M. Snead, Andrew A. Sproul, Estela Área-Gómez
This study shows that the C99 fragment of APP regulates cholesterol trafficking between the plasma membrane and ER, contributing to AD pathogenesis.
bioRxiv · Aug 21, 2019 · PreprintMolecular Biology