Author

Yimeng Xu

Columbia University Irving Medical CenterORCID 0000-0001-6290-4767Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Delfina LarreaiD· 2 shared Estela Área-GómeziD· 2 shared Rishi R. AgrawaliD· 2 shared Alison HarrodiD· 1 shared Amanda M. Snead· 1 shared Andrew A. SprouliD· 1 shared Anne-Laure CattiniD· 1 shared Annika FendleriD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Delfina LarreaORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintApr 25, 2025

Genome-wide Chromosome-specific Aneuploidy Engineering and Phenotypic Characterization with CRISPR-Taiji

Hugang Feng, Daqi Deng, Rashmi Dahiya…·Samra Turajlic

The paper introduces CRISPR-Taiji to engineer chromosome-specific aneuploidy and characterizes its transcriptomic effects, linking aneuploidy to ccRCC phenotypes.

1 citation

humanscRNA-seq

𝕏 PostBluesky

NeuroscienceCellular and Molecular NeurobiologyPeer-reviewedDec 26, 2022

Alzheimer's-associated upregulation of mitochondria-associated ER membranes after traumatic brain injury

Rishi R. Agrawal, Delfina Larrea, Yimeng Xu…·Estela Área-Gómez

The paper investigates how traumatic brain injury (TBI) increases mitochondria-associated ER membranes (MAMs) and C99 levels, linking these changes to Alzheimer's disease (AD) through lipid metabolism alterations.

15 citations

mouseproteomics

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Molecular BiologybioRxivPreprintAug 21, 2019

THE C99 FRAGMENT OF APP REGULATES CHOLESTEROL TRAFFICKING

Marta Pera, Delfina Larrea, Jorge Montesinos…·Estela Área-Gómez

This study shows that the C99 fragment of APP regulates cholesterol trafficking between the plasma membrane and ER, contributing to AD pathogenesis.

DOI 10.1101/740670

𝕏 PostBluesky