HIF-dependent Neuropeptide Y Receptor Y1 and Y5 expression sensitizes hypoxic cells to NPY stimulation
Philip John Medeiros, Sydney A. Pascetta, Sarah M. Kirsh, Baraa K. Al‐Khazraji, James Uniacke
This study shows hypoxia increases NPY1R and NPY5R expression via HIFs in breast cancer cells, making them more responsive to NPY stimulation and enhancing proliferation and migration.
Journal of Biological Chemistry · Jan 27, 2022Peer-reviewedMolecular Biology