ICM conversion to epiblast by FGF/ERK inhibition is limited in time and requires transcription and protein degradation
Sylvain Bessonnard, Sabrina Coqueran, Sandrine Vandormael‐Pournin, Alexandre Dufour, Jérôme Artus, Michel Cohen‐Tannoudji
The paper shows that FGF/ERK inhibition during a short time window can convert ICM cells into epiblast, requiring transcription and proteasome degradation.
Scientific Reports · Sep 19, 2017Peer-reviewedDevelopmental Biology