Author

Sylvia Synowiec

Endeavor Health

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Neuroscience· 4

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Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:imaging· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander DrobyshevskyiD· 4 shared Ivan V. Goussakov· 3 shared Rafael Bandeira FabresiD· 3 shared Silvia Honda TakadaiD· 2 shared Daniil Aksenov· 1 shared Daniil P. AksenoviD· 1 shared Emilia Schwenk· 1 shared Gabriela Dias Almeida· 1 shared

Activity by Year

2025-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersNeuroscience

Alexander DrobyshevskyORCID

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4 papers

Recent·Most cited

Low-frequency transcranial magnetic stimulation offers both immediate and delayed neuroprotection in neonatal hypoxia-ischemia model

Ivan V. Goussakov, Sylvia Synowiec, Alexander Drobyshevsky

This study shows that low-frequency transcranial magnetic stimulation reduces brain injury in a neonatal hypoxia-ischemia model by modulating glutamatergic transmission and providing both immediate and delayed neuroprotection.

bioRxiv · Sep 18, 2025 · PreprintNeuroscience

Comparative Analysis of Neonatal Hypomyelination Models Using Spatial Transcriptomics

Rafael Bandeira Fabres, Victor Ricardo Candido Torres da Silvia, Siwei Zhang, Sylvia Synowiec, Silvia Honda Takada, Jubao Duan, Alexander Drobyshevsky

This study compares the effects of intermittent hypoxia and hypoxia-ischemia models on myelination in neonatal mice using spatial transcriptomics, finding region-specific differences in oligodendrocyte populations and inflammatory responses.

bioRxiv · Jun 23, 2025 · PreprintNeuroscience

Differential effect of low and high frequency transcranial magnetic stimulation on cortical excitability and myelination after neonatal hypoxia in mice

Rafael Bandeira Fabres, Ivan V. Goussakov, Sylvia Synowiec, Emilia Schwenk, Vasiliy Yarnykh, Daniil Aksenov, Alexander Drobyshevsky

This study investigates the effects of low and high frequency rTMS on cortical excitability and myelination in mice after neonatal hypoxia, finding that HF-rTMS improves hypomyelination and behavioral outcomes.

bioRxiv · Jun 13, 2025 · PreprintNeuroscience

Abnormal local cortical functional connectivity due to interneuron dysmaturation after neonatal intermittent hypoxia

Ivan V. Goussakov, Sylvia Synowiec, Rafael Bandeira Fabres, Gabriela Dias Almeida, Silvia Honda Takada, Daniil P. Aksenov, Alexander Drobyshevsky

This study investigates how neonatal intermittent hypoxia affects cortical connectivity and function in mice, finding increased excitatory transmission and decreased inhibitory interneurons, leading to behavioral and cognitive impairments.

Journal of Neuroscience · Jan 31, 2025Peer-reviewedNeuroscience