Co-Delivery of Synergistic Antimicrobials with Polyelectrolyte Nanocomplexes to Treat Bacterial Biofilms and Lung Infections
J. A. Finbloom, P. Raghavan, M. Kwon, B. N. Kharbikar, M. A. Yu, T. A. Desai
This study develops AgTob-NCs, polyelectrolyte nanocomplexes co-delivering tobramycin and silver nanoparticles, showing synergistic antimicrobial activity against Pseudomonas aeruginosa biofilms and improving lung infection outcomes in mice.
bioRxiv · Nov 22, 2021Bioengineering