Author

T. Arya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

B. Casu· 2 shared C. Baron· 2 shared J. Sygusch· 2 shared A. Marinier· 1 shared B. Bessette· 1 shared C. Morin· 1 shared E. Jolicoeur· 1 shared F. Oudouhou· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBiochemistry

B. Casu

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2 papers

Recent·Most cited

Structure-based design of small molecule inhibitors of the cagT4SS ATPase Cagα of Helicobacter pylori

C. Morin, V. T. Verma, T. Arya, B. Casu, E. Jolicoeur, R. Ruel, A. Marinier, J. Sygusch, C. Baron

The paper designs small molecule inhibitors of the cagT4SS ATPase Cagα in Helicobacter pylori using structure-based approaches and identifies five potent inhibitors that inhibit ATPase activity and T4SS pili assembly.

bioRxiv · Nov 6, 2023Biochemistry

Fragment-based screening identifies inhibitors of the ATPase activity and of hexamer formation of Cagα from the Helicobacter pylori type IV secretion system

T. Arya, F. Oudouhou, B. Casu, B. Bessette, J. Sygusch, C. Baron

The paper identifies inhibitors of Cagα's ATPase activity and hexamer formation using fragment-based screening, revealing a novel mechanism for antivirulence drug development.

bioRxiv · May 20, 2018Microbiology