Expansion of gamma-butyrolactone signaling molecule biosynthesis to phosphotriester natural products
Y. Kudo, T. Awakawa, Y.-L. Du, P. A. Jordan, K. E. Creamer, P. R. Jensen, R. G. Linington, K. S. Ryan, B. S. Moore
The paper identifies the spt operon in Salinispora species as responsible for producing both saliniphostins and A-factor-like gamma-butyrolactones, revealing its broad distribution across actinomycete genera.
bioRxiv · Oct 11, 2020Biochemistry