Author

K. S. Ryan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 1

Frequent Co-Authors

Y.-L. Du· 3 shared B. S. Moore· 1 shared G. Zhao· 1 shared H.-Y. He· 1 shared J. B. Harland· 1 shared J. Lian· 1 shared J. Soler· 1 shared K. E. Creamer· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiochemistry

Y.-L. Du

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3 papers

Recent·Most cited

Structural and mechanistic views of enzymatic, heme-dependent nitrogen-nitrogen bond formation

M. A. Higgins, X. Shi, J. Soler, J. B. Harland, T. Parkkila, N. Lehnert, M. Garcia-Borras, Y.-L. Du, K. S. Ryan

This study investigates the structural and mechanistic basis of N-N bond formation by the heme-dependent enzyme PipS, revealing divergent pathways and a shared nitrenoid intermediate.

bioRxiv · Dec 15, 2023 · PreprintBiochemistry

Expansion of gamma-butyrolactone signaling molecule biosynthesis to phosphotriester natural products

Y. Kudo, T. Awakawa, Y.-L. Du, P. A. Jordan, K. E. Creamer, P. R. Jensen, R. G. Linington, K. S. Ryan, B. S. Moore

The paper identifies the spt operon in Salinispora species as responsible for producing both saliniphostins and A-factor-like gamma-butyrolactones, revealing its broad distribution across actinomycete genera.

bioRxiv · Oct 11, 2020Biochemistry

The biosynthetic gene cluster of the C-nucleoside antibiotic pyrazomycin with a rare pyrazole moiety

G. Zhao, S. Yao, K. W. Rothchild, T. Liu, Y. Liu, J. Lian, H.-Y. He, K. S. Ryan, Y.-L. Du

This study identifies the gene cluster and key enzymes involved in pyrazomycin biosynthesis in Streptomyces candidus, revealing the role of PyrR as a transcriptional activator and PyrN as a nitrogen-nitrogen bond-forming enzyme.

bioRxiv · Jul 18, 2019Biochemistry