Endothelial cells promote productive HIV infection of resting CD4+ T cells by an integrin-mediated cell adhesion-dependent mechanism
C. Card, B. Abrenica, L. R. McKinnon, T. B. Ball, R.-C. Su
This study shows endothelial cells enhance HIV infection of resting CD4+ T cells via integrin-mediated adhesion, highlighting a mechanism linking inflammation and HIV susceptibility.
bioRxiv · Jun 29, 2020Immunology