Author

T. Begum

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:multiple species· 1 Research Focus:phylogenetics / evolution· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

M. Robinson-Rechavi· 3 shared C. Bucao· 1 shared M. L. Serrano-Serrano· 1 shared P. Duchen· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 4 mutual co-author links

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3 shared papersEvolutionary Biology

M. Robinson-Rechavi

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3 papers

Recent·Most cited

Sudden shifts in expression after small-scale duplication in vertebrates and strong support for the ortholog conjecture

T. Begum, P. Duchen, C. Bucao, M. Robinson-Rechavi

The paper tests the ortholog conjecture by analyzing gene expression shifts after duplication in vertebrates, finding strong support for the conjecture and showing trait jumps affect small-scale paralogs more than genome-wide duplicates.

bioRxiv · Dec 29, 2023 · PreprintEvolutionary Biology

Performance of a phylogenetic independent contrast method and an improved pairwise comparison under different scenarios of trait evolution after speciation and duplication

T. Begum, M. L. Serrano-Serrano, M. Robinson-Rechavi

This study compares two methods for detecting functional evolution differences between orthologs and paralogs under various evolutionary scenarios, finding that both have limitations but improved pairwise comparisons are more robust.

bioRxiv · Sep 25, 2020Evolutionary Biology

Special care is needed in applying phylogenetic comparative methods to gene trees with speciation and duplication nodes

T. Begum, M. Robinson-Rechavi

The paper reanalyzes gene trees to assess phylogenetic comparative methods for studying gene function evolution, finding biases in tree calibration and supporting the ortholog conjecture with corrected methods.

bioRxiv · Aug 29, 2020Evolutionary Biology