M. L. Serrano-Serrano

Tumor-agnostic transcriptome-based classifier identifies spatial infiltration patterns of CD8+ T cells in the tumor microenvironment and predicts clinical outcome in early- and late-phase clinical trials

This study develops a transcriptome-based classifier to predict CD8+ T cell spatial infiltration patterns in the tumor microenvironment and shows its prognostic and predictive value across clinical trials.

Performance of a phylogenetic independent contrast method and an improved pairwise comparison under different scenarios of trait evolution after speciation and duplication

This study compares two methods for detecting functional evolution differences between orthologs and paralogs under various evolutionary scenarios, finding that both have limitations but improved pairwise comparisons are more robust.

Convergent changes in gene expression associated with repeated transitions between hummingbird and bee pollinated flowers

This study identifies 550 genes whose expression changes are associated with pollinator shifts in Gesneriaceae species, suggesting convergent genetic mechanisms underlie convergent floral phenotypes.

Evolutionary history of New World monkeys revealed by molecular and fossil data

This study integrates fossil and molecular data to estimate the evolutionary history of New World monkeys, revealing earlier origins and key morphological and geographic changes.