EXTENDED TUDOR-DOMAINS of the piRNA BIOGENESIS PATHWAY HAVE RNA-SPECIFIC NUCLEASE ACTIVITY
N. Dhimole, S. Zur Lage, W. Klug, T. Carlomagno
The paper identifies Qin as an endonuclease in Drosophila piRNA biogenesis, revealing its extended Tudor domains function as RNA-specific nucleases involved in 3' end processing of pre-piRNAs.
bioRxiv · Oct 25, 2021 · PreprintBiochemistry