Author

T. Crompton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Paduraru· 2 shared D. Bending· 2 shared M. Ono· 2 shared P. Prieto Martin· 2 shared B. Chain· 1 shared C. Ducker· 1 shared C.-I. Lau· 1 shared D. C. Yanez· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

A. Paduraru

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Author profile →

3 papers

Recent·Most cited

Distinct T Cell Receptor (TCR) gene segment usage and MHC-restriction between foetal and adult thymus

J. Rowell, C.-I. Lau, S. Ross, D. C. Yanez, O. Pena, B. Chain, T. Crompton

This study compares TCR gene segment usage and MHC-restriction in fetal and adult mouse thymocytes, finding distinct repertoire characteristics in fetal thymus.

bioRxiv · Sep 20, 2023Immunology

A Timer for analyzing temporally dynamic changes in transcription during differentiation in vivo

D. Bending, P. Prieto Martin, A. Paduraru, C. Ducker, E. Marzaganov, M. Laviron, S. Kitano, H. Miyachi, T. Crompton, M. Ono

The paper introduces Tocky, a tool that reveals temporal dynamics of cellular differentiation in vivo by using a fluorescent timer protein and algorithms to track molecular processes.

bioRxiv · May 15, 2018Cell Biology

A temporally dynamic Foxp3 autoregulatory transcriptional circuit controls the effector Treg programme

D. Bending, A. Paduraru, P. Prieto Martin, T. Crompton, M. Ono

This study uses a Foxp3 Timer system to analyze Foxp3 transcription dynamics in Treg cells during immune responses, showing that persistent Foxp3 transcription drives effector Treg programs and can be modulated by immunotherapy.

bioRxiv · Jan 10, 2018Immunology