Fibroblasts as an Alternative to Mesenchymal Stem Cells with Successful Treatment and Immune Modulation in EAE Model of Multiple Sclerosis
T. E. Ichim, P. O'Heeron, J. Perez, P. Liu, W. Min, S. Kesari
This study shows fibroblasts can modulate the immune system and treat EAE, a multiple sclerosis model, by inhibiting T cell activation and promoting Treg cells, suggesting their potential as an alternative to MSCs.
bioRxiv · Jun 4, 2020 · PreprintImmunology