Species-specific differences in antagonism of APOBEC3 proteins by HIV-2 and SIVsmm Vif proteins
R. Nchioua, D. Kmiec, A. Gaba, C. M. Stürzel, T. Follack, S. Patrick, A. Kirmaier, W. E. Johnson, B. H. Hahn, L. Chelico, F. Kirchhoff
This study compares the ability of HIV-2 and SIVsmm Vif proteins to counteract human APOBEC3 proteins, showing HIV-2 acquired adaptive changes for efficient counteraction in humans.
bioRxiv · Sep 8, 2020 · PreprintImmunology