Author

T. Gewering

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Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Moeller· 1 shared D. Januliene· 1 shared D. Waghray· 1 shared G. Hummer· 1 shared H. Chen· 1 shared H. Jung· 1 shared I. L. Urbatsch· 1 shared J. Zapata· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

A. Moeller

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1 paper

Recent·Most cited

Tracing the substrate translocation mechanism in P-glycoprotein

T. Gewering, D. Waghray, K. Parey, H. Jung, N. N. B. Tran, J. Zapata, P. Zhao, H. Chen, D. Januliene, G. Hummer, I. L. Urbatsch, A. Moeller, Q. Zhang

This study reveals the substrate translocation mechanism in P-glycoprotein by determining cryoEM structures and using molecular dynamics simulations to identify conformational changes in TM1 that regulate transport.

bioRxiv · Apr 28, 2022 · PreprintBiophysics