Author

T. Honjo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. Kumar· 1 shared F. Haque· 1 shared K. Chamoto· 1 shared N. A. Begum· 1 shared P. S. Chowdhury· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 4 mutual co-author links

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1 shared paperImmunology

A. Kumar

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2 papers

Recent·Most cited

XLID Syndrome Gene Med12 Promotes Ig Isotype Switching through Chromatin Modification and Enhancer RNA regulation

F. Haque, T. Honjo, N. A. Begum

This study shows Med12 promotes Ig isotype switching by regulating chromatin modification and enhancer RNA at the IgH 3RR region, with implications for X-linked intellectual disability.

bioRxiv · Jun 14, 2022Immunology

Tumors attenuating the mitochondrial activity in T cells escape from PD-1 blockade therapy

T. Honjo, A. Kumar, K. Chamoto, P. S. Chowdhury

This study identifies two mechanisms of resistance to PD-1 blockade therapy in tumors: one involving systemic immunosuppressive molecules that inhibit T cell mitochondrial activity, and another through loss of MHC class I expression.

bioRxiv · Oct 21, 2019Immunology