Collective MAPK Signaling Dynamics Coordinates Epithelial Homeostasis
T. J. Aikin, A. F. Peterson, M. J. Pokrass, H. R. Clark, S. Regot
The paper shows that MAPK activity patterns coordinate cell migration, extrusion, and proliferation to maintain epithelial tissue homeostasis through the ADAM17-EGFR paracrine signaling axis.
bioRxiv · Oct 31, 2019Cell Biology