Developmental Morphogens Direct Human Induced Pluripotent Stem Cells Towards an Annulus Fibrosus-like Cell Phenotype
A. P. Peredo, T. K. Tsinman, E. D. Bonnevie, X. Jiang, H. E. Smith, S. E. Gullbrand, N. A. Dyment, R. L. Mauck
This study identifies signaling factors that direct human iPSCs to an annulus fibrosus-like phenotype by comparing transcriptomic signatures with mature AF cells.
bioRxiv · May 6, 2022Cell Biology