Author

N. A. Dyment

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

X. Jiang· 3 shared A. F. Kuntz· 2 shared E. D. Bonnevie· 2 shared M. K. Evans· 2 shared R. L. Mauck· 2 shared A. A. Fernandes· 1 shared A. P. Peredo· 1 shared A. Srikumar· 1 shared

Activity by Year

2019-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersCell Biology

X. Jiang

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Targeting the Hedgehog Signaling Pathway to Improve Tendon-to-Bone Integration

T. B. Kamalitdinov, K. Fujino, S. K. Lang, X. Jiang, R. Madi, M. K. Evans, M. H. Zgonis, A. F. Kuntz, N. A. Dyment

This study shows that stimulating the Hedgehog pathway improves tendon-to-bone integration in mice by enhancing fibrocartilage formation and integration strength.

bioRxiv · Sep 27, 2022Bioengineering

Mechano-epigenetic regulation of extracellular matrix homeostasis via Yap and Taz

D. L. Jones, R. N. Daniels, X. Jiang, R. C. Locke, M. K. Evans, E. D. Bonnevie, A. Srikumar, M. P. Nijsure, J. D. Boerckel, R. L. Mauck, N. A. Dyment

The paper shows that mechanical tension regulates tendon cell function through Yap/Taz by modulating chromatin accessibility and catabolic gene expression.

bioRxiv · Jul 11, 2022 · PreprintCell Biology

Characterization of TGFβ-induced tendon-like structure in scaffold-free three-dimensional tendon cell culture

B.-h. Koo, Y. Lee, N. R. Park, S.-J. Heo, D. M. Hudson, A. A. Fernandes, C. S. Friday, M. W. Hast, D. T. Corr, D. R. Keene, S. F. Tufa, N. A. Dyment, K. S. Joeng

This study develops a scaffold-free 3D tendon culture system to investigate TGFβ-induced tendon-like structure formation and its effects on cell behavior and matrix organization.

bioRxiv · Jun 8, 2022 · PreprintBioengineering

Developmental Morphogens Direct Human Induced Pluripotent Stem Cells Towards an Annulus Fibrosus-like Cell Phenotype

A. P. Peredo, T. K. Tsinman, E. D. Bonnevie, X. Jiang, H. E. Smith, S. E. Gullbrand, N. A. Dyment, R. L. Mauck

This study identifies signaling factors that direct human iPSCs to an annulus fibrosus-like phenotype by comparing transcriptomic signatures with mature AF cells.

bioRxiv · May 6, 2022Cell Biology

Bone marrow stromal cells from a GDF5 origin produce zonal tendon-to-bone attachments following anterior cruciate ligament reconstruction

Y. Hagiwara, F. Dyrna, A. F. Kuntz, D. J. Adams, N. A. Dyment

This study shows that GDF5-origin mesenchymal cells contribute to zonal tendon-to-bone attachments after ACL reconstruction.

bioRxiv · Jan 27, 2019 · PreprintBioengineering