Establishment and application of unbiased in vitro drug screening assays for the identification of compounds against Echinococcus granulosus s.s.
M. Kaethner, M. Preza, T. Kaempfer, P. Zumstein, C. Tamponi, A. Varcasia, A. Hemphill, K. Brehm, B. Lundström-Stadelmann
The paper establishes in vitro culture and drug screening assays for E. granulosus s.s., showing that MMV665807, niclosamide, and nitazoxanide are effective against both E. multilocularis and E. granulosus s.s.
bioRxiv · May 2, 2023 · PreprintPharmacology & Toxicology