Author

T. Kaplan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

N. Loyfer· 2 shared A. Bograd· 1 shared A. Chase· 1 shared A. D. Mays· 1 shared A. Danov· 1 shared A. J. Kiliti· 1 shared A. Jarjoui· 1 shared A. Levy· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersMicrobiology

N. Loyfer

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Toxinome - The Bacterial Protein Toxin Database

A. Danov, O. Segev, A. Bograd, Y. Ben Eliyahu, N. Dotan, T. Kaplan, A. Levy

The paper introduces Toxinome, a comprehensive database of bacterial protein toxins and antitoxins, revealing their distribution, depletion in extreme temperature bacteria, and identification of toxin-rich genomic regions called Toxin Islands.

bioRxiv · Aug 12, 2023Microbiology

Epigenetic liquid biopsies reveal elevated vascular endothelial cell turnover and erythropoiesis in asymptomatic COVID-19 patients

R. Ben Ami, N. Loyfer, E. Cohn, G. Fialkoff, I. Sharkia, N. Bogot, D. Kochan, G. Kalak, A. Jarjoui, C. Chen-Shuali, H. Azulai, H. Barhoum, N. Arish, M. M. Greenberger, D. Velleman, , Y. Dor

This study uses epigenetic liquid biopsies to show that asymptomatic COVID-19 patients have elevated vascular endothelial cell and erythroblast turnover, indicating sub-clinical vascular and erythrocyte damage.

bioRxiv · Jul 28, 2023 · PreprintMicrobiology

Cell-free, methylated DNA in blood samples reveals tissue-specific, cellular damage from radiation treatment

M. E. Barefoot, N. Loyfer, A. J. Kiliti, M. O. Schmidt, S. Shabi-Porat, S. Jain, S. M. Roth, A. P. McDeed, N. Shahrour, E. Ballew, Y.-T. Lin, H.-H. Li, A. D. Mays, S. Rudra, A. T. Riegel, , A. Wellstein

This study uses cell-free methylated DNA in blood to detect tissue-specific damage from radiation treatment in mice and cancer patients.

bioRxiv · Apr 12, 2022Cancer Biology

Genomic Retargeting of Tumor Suppressors p53 and CTCF Promotes Oncogenesis

M. Schwartz, A. Sarusi Portugez, B. Zukerman Attia, M. Tannenbaum, O. Loza, A. Chase, Y. Turman, T. Kaplan, Z. Salah, O. Hakim

The paper identifies p53 and CTCF as key regulators of transcriptional reprogramming in early oncogenic transformation driven by HRas, showing that chromatin redistribution, not expression changes, drives malignancy.

bioRxiv · Jul 23, 2019 · PreprintCell Biology