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2 papers
Recent·Most cited
B. Ruan, Y. He, Y. Chen, E. J. Choi, Y. Chen, D. Motabar, T. Solomon, R. Simmerman, T. Kauffman, D. T. Gallagher, J. P. Orban, P. N. Bryan
The paper designs and characterizes a protein fold switching network where single amino acid substitutions can switch fold and function in proteins.
bioRxiv · Oct 26, 2022Biochemistry
Y. Chen, Y. He, B. Ruan, E. J. Choi, Y. Chen, D. Motabar, T. Solomon, R. Simmerman, T. Kauffman, D. T. Gallagher, J. Orban, P. N. BRYAN
The paper designs protein fold switches between three common small folds and identifies rules for engineering dimorphic sequences that can populate multiple folds.
bioRxiv · May 18, 2021 · PreprintBiophysics