Mrs4 loss of function in fungi during adaptation to the cystic fibrosis lung
D. Murante, E. Demers, T. Kurbessoian, M. Ruzic, A. Ashare, J. E. Stajich, D. A. Hogan
The paper identifies MRS4 mutations in fungi associated with cystic fibrosis lung infections, showing they confer a fitness advantage by enhancing iron acquisition in iron-limited environments.
bioRxiv · Apr 5, 2023Microbiology