Author

T. M. De-Simone

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

C. d. Q. Sacramento· 1 shared C. R. Alves· 1 shared D. W. Provance-Jr· 1 shared F. Souza-Silva· 1 shared G. C. Lechuga· 1 shared J. R. Temerozzo· 1 shared M. C. d. S. Pereira· 1 shared M. R. d. O. Trugilho· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

C. d. Q. Sacramento

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1 paper

Recent·Most cited

SARS-CoV-2 proteins bind heme and hemoglobin

S. G. De-Simone, G. C. Lechuga, F. Souza-Silva, C. d. Q. Sacramento, M. R. d. O. Trugilho, R. H. Valente, P. Napoleao-Pego, S. d. S. G. Dias, N. Fintelman-Rodrigues, J. R. Temerozzo, N. Carels, C. R. Alves, M. C. d. S. Pereira, D. W. Provance-Jr, T. M. De-Simone

This paper shows SARS-CoV-2 proteins bind hemin and hemoglobin, with hemin inhibiting viral replication and interacting with the Spike protein's RBD region.

bioRxiv · Apr 16, 2021 · PreprintBiochemistry