Evidence of Disrupted-in Schizophrenia 1 (DISC1) as an arsenic binding protein and implications regarding its role as a translational activator
M. Watanabe, T. M. Khu, G. Warren, J. Shin, C. E. Stewart, J. Roche
This study shows DISC1 binds arsenic via a C-terminal cysteine motif and suggests it acts as a sensor and translational modulator in the Akt/mTOR pathway.
bioRxiv · Jun 14, 2023 · PreprintBiophysics